In order to efficiently develop the super-low permeability reservoirs in Zhenbei Area of Ordos Basin, this paper begins with the sensitivity evaluation on Chang 3 Member sandstone reservoir of Yanchang Formation through the dynamic core flow test. The results show that the super-ow permeability reservoir has the characteristics of weak water sensitivity, low velocity sensitivity, weak salt sensitivity, medium strong pressure sensitivity and very strong acid sensitivity. Combined with scanning electron microscopy (SEM) analysis, energy spectrum analysis and X diffraction means, this paper finds out the type, content, shape and distribution characteristics of the sensitivity mineral in low permeability reservoir and deeply analyzes the formation mechanism of sensitivity of low permeability reservoir. Finally, the relative problems existed in core flow test for super-low permeability reservoir are discussed. It is considered that there are shortcomings in equipment and instrument, experimental method and evaluation at present, needing further improvement and establishment of the sensitivity evaluation standard.