吡啶-对甲苯磺酸功能化离子液体催化2-萘甲醚的酰化

Acylation Reaction on the 2-Methoxynaphthalene Catalyzed by Pyridine-Toluene-p-Sulfonic Acid Functionalized Ionic Liquid

辽宁石油化工大学 化学与材料科学学院,辽宁 抚顺 113001

College of Chemistry & Material Science Engineering,Liaoning Shihua University,Fushun Liaoning 113001,China

关键词: 离子液体, 2-萘甲醚, , F-C酰基化, , 催化, , 正交试验

Pyridine-sulfonic acid functionalized ionic liquid([PY-BS] [TsO]) is prepared by the reaction of p-toluenesulfonic acid with sulfonic groups amphoteric salt(PY-BS) that is prepared by the reaction of Pyridine with 1,4butyl sultone. Then, [PY-BS][TsO] ionic liquid can be characterized by IR, NMR. And it is chosen as the catalyst and solvent in the Friedel-Craft acylation of 2-methoxynaphthalene optimizing the reaction conditions by orthogonal experiment of L9(34). The orthogonal experiment result shows that the conversion of 2-methoxynaphthalene (2-MN) reaches 90.7% and the selectivity of 2-methoxy-1-acetyl naphthalene as the main products is 99.4% in the follwing conditions that the 2methoxynaphthalene is 5 mmol, the mol ratio of 2-methoxynaphthalene/acetic anhydride is 1∶5, ionic liquid is 0.3 g and reaction time is 6.0 h at 120 ℃. The main factors affecting the reaction rate and product selectivity are the reaction time and temperature.

辽宁省自然科学基金项目(2015020196);辽宁省大学生创新创业项目(201510148047)。

10.3969/j.issn.1672-6952.2017.02.002