连续流微反应器内蒽醌硝化反应规律研究

Study on the Continuous⁃Flow Nitration Process of Anthraquinone in Microreactor

主凯 倪泽雨 黄益平 黄晶晶 蔡磊 周峰 胡猛

Kai ZHU Zeyu NI Yiping HUANG Jingjing HUANG Lei CAI Feng ZHOU Meng HU

中建安装集团有限公司，江苏 南京 210023 淮阴工学院 化工学院，江苏 淮安 223003

China Construction Industrial & Energy Engineering Group Co. ，Ltd. ，Nanjing Jiangsu 210023，China Faculty of Chemical Engineering，Huaiyin Institute of Technology，Huai，an Jiangsu 223003，China

蒽醌类染料是染料行业用量仅次于偶氮染料的第二大类染料，通过蒽醌硝化反应制备的硝基蒽醌是合成各类蒽醌类染料的重要原料之一。采用热质传递性能优异的微反应器，研究了蒽醌连续硝化反应过程中反应温度、蒽醌体积流量、n（HNO3）/n（蒽醌）、蒽醌浓度、停留时间及硫酸质量分数等关键工艺参数对蒽醌硝化反应的影响。结果表明，在蒽醌硝化反应过程中，一硝化和二硝化反应竞争显著；调节过程工艺参数，在促进蒽醌转化率的同时，会显著影响一硝化和二硝化产物的比例。充分利用微反应器的优势精确调控过程参数，是提高单一硝化产物选择性的有效措施。

Anthraquinone dyes are the second most significant dyes in the dye industry after azo dyes.Nitroanthraquinone prepared by the nitration of anthraquinone,is one of the important raw materials for the synthesis of various types of anthraquinone dyes.In this study,a microreactor with excellent heat and mass transfer properties was utilized to investigate the continuous?flow nitration process of anthraquinone.The effects of key process parameters such as reaction temperature,volume flow rate,molar ratio of nitric acid to anthraquinone,anthraquinone concentration,residence time,and sulfuric acid intensity on the nitration process were examined.The results showed that the competition between mono? and di?nitrification reactions during anthraquinone nitrification was significant, and the adjustment of process parameters would significantly affect the ratio of mono? and di?nitrification products while promoting the conversion rate of anthraquinone.The full use of the advantages of microreactors to precisely regulate the process parameters is an effective measure to improve the selectivity of the target nitration product.

中建股份科技研发项目(CSCEC?2021?Z?51);建设系统科技计划项目(Ks2253)

10.12422/j.issn.1006-396X.2024.01.002